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The Importance of Neoplasia Research in Fish

| İbrahim Cengizler |

Year:2025| Vol:4| No:1| PP 3-9
Abstract
Neoplasia is observed in fish, which constitute the lowest group of vertebrates, as in other vertebrate species. Although neoplasia (also referred to as fish oncology) is not very common, it can occur in different tissues and due to various factors in fish. Investigating, diagnosing, and treating neoplasia in fish is particularly challenging, as fish spend their entire lives in aquatic environments. Environmental factors and pollution are known to be among the major causes of neoplasia in fish. Therefore, an increase in neoplastic cases may render fish useful as indicators of environmental pollution. In addition, fish can be used as model and experimental animals in oncological research for humans and other vertebrates. The relatively low incidence of neoplasia in cartilaginous fish does not indicate resistance to cancer. Nevertheless, there is a clear need for more detailed research on neoplasia in fish.

Keywords
Fish; Neoplasia; Environmental; Pollution
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References
  1. Sarihan, E. and Cengizler, .Ibrahim Temel balik anatomisi ve fizyolojisi. Nobel Kitabevi, 2006.
  2. Ferraro, E.; Harrison, S. H; Duke, E.; Troan, B.; Boddy, A.; Abegglen, L. M and Harrison, T. M Retrospective study of the prevalence, histopathology, therapy, and survival time of neoplastic disease in fish. In Animals, 14 (3): 464, 2024.
  3. Cengizler, .Ibrahim Balik Hastaliklari. Nobel Kitabevi, 2006.
  4. Groff, J. M Neoplasia in fishes. In Veterinary Clinics: Exotic Animal Practice, 7 (3): 705-756, 2004.
  5. Vergneau-Grosset, C.; Nadeau, M-E. and Groff, J. M Fish oncology: diseases, diagnostics, and therapeutics. In Veterinary Clinics: Exotic Animal Practice, 20 (1): 21-56, 2017.
  6. McAloose, D.; Colegrove, K. M and Newton, A. L Wildlife necropsy. In Pathology of wildlife and zoo animals, pages 1-20, Elsevier, 2018.
  7. Blazer, V. S; Fournie, J. W; Wolf, J. C and Wolfe, M. J Manual for the microscopic diagnosis of proliferative liver and skin lesions in the brown bullhead.
  8. Keel, M K.; Terio, K. A and McAloose, D. Canidae, ursidae, and ailuridae. In Pathology of wildlife and zoo animals, pages 229-261, Elsevier, 2018.
  9. Kimura, I.; Kinae, N.; Kumai, H.; Yamashita, M.; Nakamura, G.; Ando, M.; Ishida, H. and Tomita, I. Environment: Peculiar pigment cell neoplasm in fish. In Journal of Investigative Dermatology, 92 (5): S248-S254, 1989.
  10. Kn"usel, F O.; Doherr, MG; Kn"usel, R; Wahli, T and Schmidt-Posthaus, H Risk factors for development of internal neoplasms in koi carp Cyprinus carpio koi. In Diseases of Aquatic Organisms, 114 (3): 199-207, 2015.
  11. Loprinzi, CL; Levitt, R; Barton, DL; Sloan, JA; Atherton, PJ; Smith, DJ; Dakhil, SR; Moore Jr, DF; Krook, JE; Rowland Jr, KM and thers, Haifischknorpel: Wirklich das Wunder-mittel gegen Krebs?. In Cancer, 104: 176-182, 2005.
  12. Cho, J. and Kim, Y. Sharks: a potential source of antiangiogenic factors and tumor treatments. In Marine Biotechnology, 4 (6): 521-525, 2002.
  13. Ostrander, G. K; Cheng, K. C; Wolf, J. C and Wolfe, M. J Shark cartilage, cancer and the growing threat of pseudoscience. In Cancer research, 64 (23): 8485-8491, 2004.
  14. Robbins, R.; Bruce, B. and Fox, A. First reports of proliferative lesions in the great white shark, Carcharodon carcharias L., and bronze whaler shark, Carcharhinus brachyurus G"unther. In Journal of Fish Diseases, 37 (11), 2014.
  15. McAloose, D. and Newton, A. L Wildlife cancer: a conservation perspective. In Nature reviews cancer, 9 (7): 517-526, 2009.
  16. Bossart, G. D Emerging diseases in marine mammals: from dolphins to manatees. In Microbe-American Society for Microbiology, 2 (11): 544, 2007.
  17. Kibenge, F. SB; Baldisserotto, B. and Chong, R. S-M. Aquaculture Pathophysiology: Volume I. Finfish Diseases. Academic Press, 2022.